It has been found to be both safe and effective. When administered in prescribed amounts by a qualified practitioner, the chances of experiencing adverse reactions to bio-oxidative therapies are extremely small. For example, a German study on 384,775 patients evaluating the adverse side effects of over five million medically-administered ozone treatments found that the rate of adverse side effects was only 0.0007 per application. This figure is far lower than any other type of medical therapy.
It has been estimated that over ten million people have been given bio-oxidative therapies over the past seventy years to treat over fifty different diseases. As cited before, they include heart and blood vessel diseases, diseases of the lungs, infectious diseases, and immune-related disorders. In some cases, bio-oxidative therapies are administered alone, while in others, they are used in addition to traditional medical procedures (such as surgery or chemotherapy) or as adjuncts to alternative health practices like megavitamin therapy, acupuncture or herbal medicine.